Muscarinic Agonists Emraclidine/Phase 2 trial failed/Muscarinic drugs not highly effective?
IntroductionThe results of Emraclidine’s Phase 2 trials have been released. Emraclidine is an antipsychotic drug that ac...
Muscarinic Agonists 
Articles for Beginners Five Advantages of Taking KarXT (Cobenfy)/ A Summary Article for Beginners
IntroductionA new antipsychotic drug called KarXT (Cobenfy) was recently approved by the FDA. In the U.S., it will be la...
Muscarinic Agonists 【NBI-1117568】Detailed analysis of Phase 2 results data/More effective than olanzapine
IntroductionThe results of the Phase 2 study of NBI-1117568 are now available. I will discuss the resulting data. The re...
Important Articles 21 Drugs for Cognitive and Negative Symptoms of Schizophrenia in 2024 【Revised 2024.5.20】
IntroductionThis article summarizes new drugs in development that may help with cognitive dysfunction and negative sympt...
Muscarinic Agonists KarXT(Cobenfy) has a high long-term efficacy/ Long-term study results/EMERGENT-4
IntroductionThe results of a long-term study of KarXT(Cobenfy) were recently published, and I thought the long-term effi...
Important Articles List of antipsychotics under development in 2024【Revised 2024.1.26】
IntroductionI'll do as much research as I can about the antipsychotics in development in the list below, and I'll write ...
Investigational Drugs Brilaroxazine/High Efficacy & Mild Side Effects
IntroductionIn October 2023, the results of a Phase 3 study of brilaroxazine were announced. Brilaroxazine is an antipsy...
Articles for Beginners Innovative Schizophrenia Drugs【Summary part 2】Ulotaront, etc.
Introduction（This article is a translation of an article for Japanese readers.）In this article, following on from (part ...
Ulotaront 【Ulotaront】U.S. Phase 3 Studies Failed. What’s Next? / Clinical Trial Data
IntroductionThe results of the Phase 3 trials of Ulotaront were released in July 2023. Two Phase 3 trials were both fail...
Articles for Beginners Innovative Schizophrenia Drugs【Summary part 1】Muscarinic Agonists
IntroductionIn this article and the next, I will summarize innovative schizophrenia drugs that will be released in the f...
Muscarinic Agonists EMERGENT-3【KarXT(Cobenfy)】Efficacy Compared to Current Drugs in Phase3
IntroductionNow that the results of KarXT(Cobenfy)'s second Phase 3 trial are in, I have a lot to think about. This tria...
Ulotaront A lot of benefits of taking【Ulotaront】: A new antipsychotic drug
IntroductionUlotaront acts as a TAAR1 agonist and a 5HT1A receptor agonist.I found a review article that describes the a...
Ulotaront 【Ulotaront part 2】Phase 2 trial was successful. / Clinical Trial Data
IntroductionIn Part2, I will write about the efficacy of Ulotaront, one of the most anticipated antipsychotic drugs of t...
Ulotaront 【Ulotaront part 1】Promising TAAR1 agonist
IntroductionI have written several times that I am most excited about muscarinic agonists such as KarXT, Emraclidine, an...
Important Articles Positive and Negative Syndrome Scale(PANSS, Scale used to measure efficacy)
IntroductionWhat is PANSS?PANSS (Positive and Negative Syndrome Scale) is a scale used to measure the severity of schizo...